All of your hormones and hormonal glands have an intricate relationship with each other, giving each other feedback and having an influence on each others levels. A little bit of a one hormone going up can cause another to go down, and so imbalances can have a flow on effect which can cause many symptoms.

A major connection to consider is the link between your thyroid health and your oestrogen and progesterone levels.

We know excessive levels of oestrogen can have an impact on thyroid health, with too much oestrogen making your thyroid balance go out of whack, but how does it actually do this?

Essentially…

Oestrogen can raise thyroid binding globulin, which will lower free thyroid hormone levels.

This can be a problem for women who are on artificial hormones such as the oral contraceptive pill, or for women who have higher than normal levels of oestrogen in their system.

Typically this will show up as heavy periods and longer menstrual cycles. The increased oestrogen results in a relative deficiency of progesterone which is responsible for the thinning of the endomentrial lining. It can also impact on the coagulatory factors in the blood which control excessive bleeding.

Potenially thyroid problems can also contribute towards amenorrhoea, when your period disappears for a while.

Thyroid issues can also cause oestrogen to be bound up and carried away less than it should be, as thyroid problems can indirectly cause a reduced level of Sex Hormone Binding Globulin (SHBG) which would typically bind to excess levels of hormones such as oestrogen.

Oestrogen imbalance can be the missing piece of the puzzle for many women (and men) who have issues with T3 balance. It is a cycle that feeds itself until the original cause of the thyroid imbalance or oestrogen excess is addressed.

High Oestrogen -> Increased thyroid binding globulin -> low free thyroid hormone levels.

Low Thyroid Function -> Low SHBG -> High Oestrogen

An interesting action of oestrogen is that it can increase the proliferation of thyroid cells. This isn’t always a bad thing, as it can be helpful to regulate thyroid function and help the repair of the thyroid gland when oestrogen is in normal ranges. However in excess this could result in an increased risk of autoimmune thyroid disease or thyroid cancer.

Now we know that oestrogen isn’t the only female hormone. Progesterone is another important hormone for women, and it too has a connection with the thyroid hormones.

The thyroid – progesterone connection goes two ways. Thyroid helps stimulate release of progesterone from the luteal cells. Given this, we can consider that for some women who appear to have progesterone deficiency they may have underlying issues with their T3 hormone as the cause.

And progesterone deficiency can impact on the conversion of T4 to T3 via reduced deiodinase 2 activity. So for women who are post-menopausal, who have had an oophorectomy (ovaries removed surgically) or do not ovulate regularly (e.g in Hypothalamic Amenorrhoea or PCOS) the state of their thyroid is something to consider.

Imbalances in both progesterone and oestrogen can impact your immune system balance which can increase your risk of autoimmune disease, an issue which is common for thyroid problems.

If you suspect that you have an issue with your hormones and would like some holistic support or perhaps you would like to discuss testing options, contact your health care practitioner to discuss your options.

Book an Appointment

Extra reading

Your Thyroid Needs Iron

Heavy Periods

MTHFR and your Thyroid

Thyroid Problems After Having a Baby

Thyroid Health – Part 1

Understanding Underactive Thyroid – Webinar

References

Role of estrogen in thyroid function and growth regulation.  https://doi.org/10.4061/2011/875125

Clinical review: Thyroid dysfunction and effects on coagulation and fibrinolysis: a systematic review. https://doi.org/10.1210/jc.2007-0199

An evidence for the transcriptional regulation of iodothyronine deiodinase 2 by progesterone in ovarectomized rats. https://doi.org/10.1007/s13105-013-0307-y

Menorrhagia and hypothyroidism. Evidence supports association between hypothyroidism and menorrhagia. https://doi.org/10.1136/bmj.https://doi.org/10.1136/bmj.320.7235.649

Menstrual disturbances in various thyroid diseases. https://doi.org/10.1507/endocrj.k10e-216

Thyroid disease and female reproduction. https://doi.org/10.1111/j.1365-2265.2007.02752.x

The post Thyroid Problems and Oestrogen appeared first on Alison Mitchell Naturopath.

This article follows on from the previous article, which discussed the thyroid gland and the differences between and over and underactive thyroid. In this article I am talking about how an issue with the thyroid can cause imbalances in the rest of the endocrine system, in particular the endocrine system.

Thyroid Health

 The endocrine system

Endocrine is the term used for the complex system of glands and their secretions (hormones).  The endocrine system includes the glands (pituitary, thyroid, para-thyroid, adrenal and pineal) as well as organs and tissues which are able to produce hormones (fat tissue, the hypothalamus, ovaries, testes, pancreas, thymus, kidneys, stomach, liver, small intestine, skin, heart and placenta).  There is a cross-over between different systems such as in the digestive system which includes organs also classed as endocrine.

 In the previous newsletter I gave you an overview of the thyroid and the differences between hyperthyroidism and hypothyroidism.  In this newsletter I want to give you some information about the ways in which the thyroid can affect the endocrine system over all.

 The endocrine system is all connected and an imbalance in one particular organ or gland can disrupt everything else.  One of the biggest ways that we can see this is looking at the impact of stress.  Have you noticed that when you’re stressed you’re more likely to catch a cold (remember the thymus is an endocrine organ and has a big role in our immunity), break out (the skin is responsive to hormones, pumping out more oil to feed the bacteria that causes acne) and your digestive system can get upset too(the stomach, pancreas and liver are all endocrine organs)!

Thyroid health and the reproductive system.

The thyroid gland is another big player in keeping our endocrine system balanced.  One of the most common things that an unhappy thyroid will affect is the reproductive system.

In both men and women hypothyroidism can affect libido. In men, they may experience infertility and mpotence.  In women they may experienced an irregular menstrual cycle or irregular bleed.  Fertility is also greatly affected by the thyroid gland especially in women with autoimmune thyroid disease.  It may result in not being able to conceive altogether or an increase in miscarriages.  In women of fertile age, autoimmune thyroid disease is the most common cause of hypothyroidism.

How?

• A reduction in thyroid function will leave to elevated TSH, and depressed secretion of dopamine, leading to elevated prolactin levels.
• Elevated prolactin levels, also known as hyperprolactinaemia is implicated in 1-3% of women with problems ovulating.
• Hypothyroidism interferes with an important hormone for the development of the egg and ovulation – gonadotrophin-releasing hormone (GnRH).
• Hypothyroidism can lead to a delay in luteinising hormone (LH) which causes ovulation and stimulates the secretion of progesterone.  Because of this is can cause a reduction in progesterone synthesis.
• Thyroid antibodies which can be present in both hyperthyroidism and hypothyroidism can affect fertility due to it’s impact on implantation and increasing the risk of miscarriage.  In some people antibodies
  can be present without having any signs of thyroid dysfunction.  Thyroid antibodies can be managed with herbs that modulate the immune system.

Thyroid dysfunction affects the hormones needed for healthy egg development and ovulation, which affects fertility and creates an imbalance in other reproductive hormones.

If you are having difficulty conceiving it is important to assess thyroid function and screen for the presence of antibodies to rule out any complicating involvement from this gland.

If you believe that you have a thyroid problem, don’t despair.  We can assess for and manage a thyroid imbalance using safe, effective natural remedies.

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The post Thyroid Health – Part 2 appeared first on Alison Mitchell Naturopath.